metschnikowiaceae cah: functional enrichment (loss)
One-sided hypergeometric test per term; Benjamini-Hochberg FDR within each scope, level and vocabulary. Candidates are the loss candidates: gene families present in the OUT group and absent from the IN group. Universe: proteome. Background clustered: True (74857 sequences in 21615 clusters, mmseqs easy-cluster --min-seq-id 0.3 -c 0.8). Family level: one unit per candidate family and per background cluster.
Sources: Pfam: 2026-01-27-Pfam38.2; InterPro entries: 110.0; GO: releases/2026-07-26; analysis generated 2026-10-12T18:21:36. Source tables: studies/fungi/metschnikowiaceae_cah/analysis/enrichment/outputs/loss/proteome_clustered.
Full record: PROVENANCE. Run report: report.html.
- Annotation provenance is not fully recorded: PROVENANCE.yaml lists the per-species annotation files and their checksums, but not the UniProt release they come from.
- GO results are secondary. GO annotations include computational evidence (IEA, IBA); the GO evidence column shows if a term has non-IEA support.
- Candidate families (pipeline clustering of candidates) and background clusters (mmseqs clustering of the background proteome) are made by different runs, so family-level counts are not fully comparable.
- Low annotation: the candidate set has less than 50% annotation for GO 48.4%. Enrichment for these vocabularies has low power.
Summary figure
Annotation coverage
Fraction of proteins with at least one term per vocabulary. Universe = all proteins of the species; candidates = the candidate set.
| Species | Set | Proteins | Pfam | Pfam clan | InterPro | GO | Any |
|---|---|---|---|---|---|---|---|
| Candalbi | universe | 6040 | 84.2% | 65.5% | 88.1% | 82.9% | 90.2% |
| Candalbi | candidates | 15 | 66.7% | 53.3% | 73.3% | 60.0% | 73.3% |
| Candtrop | universe | 6226 | 81.9% | 64.7% | 85.9% | 76.9% | 86.3% |
| Candtrop | candidates | 15 | 66.7% | 53.3% | 73.3% | 60.0% | 73.3% |
| Loddelon | universe | 5779 | 82.1% | 64.8% | 86.1% | 77.5% | 86.6% |
| Loddelon | candidates | 8 | 50.0% | 37.5% | 75.0% | 50.0% | 75.0% |
| Meyeguil | universe | 5919 | 85.5% | 68.6% | 89.1% | 80.3% | 89.4% |
| Meyeguil | candidates | 9 | 55.6% | 44.4% | 66.7% | 33.3% | 66.7% |
| Debahans | universe | 6284 | 83.2% | 65.2% | 86.6% | 78.1% | 86.8% |
| Debahans | candidates | 14 | 50.0% | 35.7% | 64.3% | 50.0% | 64.3% |
| Schestip | universe | 5797 | 87.4% | 69.0% | 90.8% | 82.2% | 91.1% |
| Schestip | candidates | 16 | 56.2% | 43.8% | 75.0% | 37.5% | 75.0% |
| Spatpass | universe | 5973 | 83.9% | 66.2% | 87.4% | 78.4% | 87.7% |
| Spatpass | candidates | 16 | 56.2% | 50.0% | 68.8% | 50.0% | 68.8% |
| Diutrugo | universe | 5811 | 81.2% | 64.5% | 84.9% | 75.5% | 85.2% |
| Diutrugo | candidates | 8 | 87.5% | 62.5% | 100.0% | 62.5% | 100.0% |
| Komaphaf | universe | 5075 | 87.7% | 68.1% | 90.6% | 82.5% | 90.9% |
| Komaphaf | candidates | 17 | 76.5% | 58.8% | 76.5% | 52.9% | 76.5% |
| Ogatpara | universe | 5319 | 88.8% | 71.1% | 91.9% | 84.1% | 92.2% |
| Ogatpara | candidates | 19 | 79.0% | 63.2% | 79.0% | 52.6% | 84.2% |
| Kuracaps | universe | 6027 | 84.6% | 67.4% | 88.0% | 79.2% | 88.3% |
| Kuracaps | candidates | 15 | 73.3% | 40.0% | 80.0% | 53.3% | 80.0% |
| Pichkudr | universe | 5146 | 86.7% | 68.2% | 90.4% | 81.9% | 90.7% |
| Pichkudr | candidates | 15 | 66.7% | 40.0% | 73.3% | 26.7% | 73.3% |
| Pachtann | universe | 5643 | 85.8% | 67.1% | 88.9% | 80.3% | 89.3% |
| Pachtann | candidates | 15 | 66.7% | 46.7% | 73.3% | 40.0% | 73.3% |
| ALL_OUT | universe | 75039 | 84.7% | 66.9% | 88.3% | 79.9% | 88.8% |
| ALL_OUT | candidates | 182 | 65.9% | 48.9% | 74.7% | 48.4% | 75.3% |
Tests summary
Per vocabulary: terms with FDR < 0.05 / terms tested. Protein level counts proteins; family level counts candidate families and background clusters.
| Scope | Level | Cand. units | Pfam sig / tested | Pfam clan sig / tested | InterPro sig / tested | GO sig / tested |
|---|---|---|---|---|---|---|
| whole_set | family | 102 | 6 / 1160 | 3 / 315 | 15 / 2262 | 2 / 4097 |
| whole_set | protein | 182 | 13 / 4099 | 8 / 474 | 32 / 8561 | 43 / 6985 |
| Candalbi | family | 14 | 0 / 168 | 0 / 182 | 0 / 489 | 0 / 2836 |
| Candalbi | protein | 15 | 0 / 249 | 0 / 204 | 0 / 672 | 0 / 2967 |
| Candtrop | family | 14 | 0 / 182 | 0 / 183 | 0 / 507 | 0 / 2468 |
| Candtrop | protein | 15 | 0 / 255 | 1 / 194 | 0 / 666 | 1 / 2611 |
| Debahans | family | 14 | 0 / 173 | 1 / 182 | 0 / 494 | 0 / 2523 |
| Debahans | protein | 14 | 0 / 240 | 1 / 204 | 0 / 646 | 0 / 2649 |
| Diutrugo | family | 7 | 0 / 153 | 0 / 182 | 0 / 451 | 0 / 1895 |
| Diutrugo | protein | 8 | 0 / 224 | 0 / 205 | 0 / 595 | 0 / 2035 |
| Komaphaf | family | 16 | 0 / 136 | 0 / 172 | 0 / 426 | 0 / 2421 |
| Komaphaf | protein | 17 | 0 / 181 | 0 / 186 | 0 / 530 | 0 / 2522 |
| Kuracaps | family | 15 | 0 / 167 | 0 / 186 | 0 / 479 | 0 / 2471 |
| Kuracaps | protein | 15 | 0 / 237 | 0 / 201 | 0 / 622 | 0 / 2583 |
| Loddelon | family | 7 | 0 / 168 | 0 / 180 | 0 / 478 | 0 / 2385 |
| Loddelon | protein | 8 | 0 / 225 | 0 / 200 | 0 / 601 | 0 / 2496 |
| Meyeguil | family | 9 | 0 / 175 | 0 / 178 | 0 / 508 | 0 / 2480 |
| Meyeguil | protein | 9 | 0 / 226 | 0 / 190 | 0 / 628 | 0 / 2576 |
| Ogatpara | family | 19 | 0 / 150 | 0 / 180 | 0 / 461 | 0 / 2456 |
| Ogatpara | protein | 19 | 0 / 203 | 0 / 192 | 0 / 582 | 0 / 2574 |
| Pachtann | family | 15 | 0 / 167 | 0 / 176 | 0 / 471 | 0 / 2079 |
| Pachtann | protein | 15 | 0 / 227 | 1 / 190 | 0 / 606 | 0 / 2230 |
| Pichkudr | family | 15 | 0 / 143 | 1 / 175 | 0 / 418 | 0 / 2015 |
| Pichkudr | protein | 15 | 0 / 202 | 1 / 191 | 0 / 543 | 0 / 2138 |
| Schestip | family | 15 | 0 / 163 | 1 / 182 | 0 / 484 | 0 / 2495 |
| Schestip | protein | 16 | 0 / 239 | 1 / 203 | 0 / 647 | 0 / 2640 |
| Spatpass | family | 15 | 0 / 171 | 0 / 183 | 0 / 497 | 0 / 2476 |
| Spatpass | protein | 16 | 0 / 224 | 0 / 196 | 0 / 617 | 1 / 2582 |
Top 25 Pfam terms (whole set, family level)
25 rows shown, ordered by FDR then p-value; 6 have FDR < 0.05 (bold).
| Term | Name | k / N cand. | n / M bg | Fold | FDR (BH) |
|---|---|---|---|---|---|
| PF11001 | AFUB_07903_YDR124W_hel: YDR124W-like, helical bundle domain | 11 / 73 | 11 / 13892 | 190.301 | 4.45e-23 |
| PF29444 | KH_FAR1_2nd: FAR1 C-terminal domain | 8 / 73 | 10 / 13892 | 152.241 | 6.76e-15 |
| PF29445 | PH_FAR1: FAR1 PH domain | 8 / 73 | 10 / 13892 | 152.241 | 6.76e-15 |
| PF29452 | FAR1_N: FAR1 N-terminal domain | 7 / 73 | 19 / 13892 | 70.111 | 1.14e-09 |
| PF02148 | zf-UBP: Zn-finger in ubiquitin-hydrolases and other protein | 4 / 73 | 9 / 13892 | 84.578 | 2.01e-05 |
| PF12550 | GCR1_C: Transcriptional activator of glycolytic enzymes | 4 / 73 | 24 / 13892 | 31.717 | 0.001 |
| PF01753 | zf-MYND: MYND finger | 2 / 73 | 6 / 13892 | 63.434 | 0.058 |
| PF23187 | UBX7_N: UBX7 N-terminal domain | 2 / 73 | 6 / 13892 | 63.434 | 0.058 |
| PF30147 | SSP1: Sporulation-specific protein 1 | 2 / 73 | 7 / 13892 | 54.372 | 0.072 |
| PF00443 | UCH: Ubiquitin carboxyl-terminal hydrolase | 3 / 73 | 39 / 13892 | 14.639 | 0.129 |
| PF01569 | PAP2: PAP2 superfamily | 2 / 73 | 11 / 13892 | 34.6 | 0.153 |
| PF00789 | UBX: UBX domain | 2 / 73 | 14 / 13892 | 27.186 | 0.230 |
| PF00856 | SET: SET domain | 2 / 73 | 25 / 13892 | 15.224 | 0.674 |
| PF28255 | CIP1_helical: CIP1 helical domain | 1 / 73 | 5 / 13892 | 38.06 | 1.000 |
| PF01588 | tRNA_bind: Putative tRNA binding domain | 1 / 73 | 6 / 13892 | 31.717 | 1.000 |
| PF03171 | 2OG-FeII_Oxy: 2OG-Fe(II) oxygenase superfamily | 1 / 73 | 6 / 13892 | 31.717 | 1.000 |
| PF07962 | Swi3: Replication Fork Protection Component Swi3 | 1 / 73 | 6 / 13892 | 31.717 | 1.000 |
| PF08320 | PIG-X: PIG-X / PBN1 | 1 / 73 | 6 / 13892 | 31.717 | 1.000 |
| PF08585 | RMI1_N_C: RMI1, N-terminal OB-fold domain | 1 / 73 | 6 / 13892 | 31.717 | 1.000 |
| PF10403 | BHD_1: Rad4 beta-hairpin domain 1 | 1 / 73 | 6 / 13892 | 31.717 | 1.000 |
| PF12927 | DUF3835: Domain of unknown function (DUF3835) | 1 / 73 | 6 / 13892 | 31.717 | 1.000 |
| PF29059 | AIM39_C: AIM39 C-terminal domain | 1 / 73 | 6 / 13892 | 31.717 | 1.000 |
| PF29704 | YDL186W: Uncharacterised protein YDL186W | 1 / 73 | 6 / 13892 | 31.717 | 1.000 |
| PF07954 | DUF1689: Protein of unknown function (DUF1689) | 1 / 73 | 7 / 13892 | 27.186 | 1.000 |
| PF10404 | BHD_2: Rad4 beta-hairpin domain 2 | 1 / 73 | 7 / 13892 | 27.186 | 1.000 |
Top 25 InterPro terms (whole set, family level)
25 rows shown, ordered by FDR then p-value; 15 have FDR < 0.05 (bold).
| Term | Name | k / N cand. | n / M bg | Fold | FDR (BH) |
|---|---|---|---|---|---|
| IPR021264 | Family:Subtelomeric hrmA-associated cluster protein AFUB_079030/YDR124W-like | 11 / 81 | 11 / 15006 | 185.259 | 6.32e-23 |
| IPR047092 | Domain:Subtelomeric hrmA-associated cluster protein AFUB_079030/YDR124W-like, helical bundle domain | 11 / 81 | 11 / 15006 | 185.259 | 6.32e-23 |
| IPR063245 | Domain:FAR1, PH domain | 8 / 81 | 10 / 15006 | 148.207 | 1.27e-14 |
| IPR063947 | Domain:FAR1, vWA-like domain | 8 / 81 | 10 / 15006 | 148.207 | 1.27e-14 |
| IPR063968 | Domain:FAR1, N-terminal domain | 7 / 81 | 19 / 15006 | 68.253 | 2.22e-09 |
| IPR001607 | Domain:Zinc finger, UBP-type | 4 / 81 | 9 / 15006 | 82.337 | 3.67e-05 |
| IPR050587 | Family:GNT1/Glycosyltransferase 8 | 4 / 81 | 10 / 15006 | 74.104 | 5.22e-05 |
| IPR052146 | Family:High-osmolarity-induced transcription | 4 / 81 | 18 / 15006 | 41.169 | 6.43e-04 |
| IPR022210 | Domain:Transcription activator GCR1-like domain | 4 / 81 | 24 / 15006 | 30.877 | 0.002 |
| IPR050869 | Family:Histone-lysine N-methyltransferase | 3 / 81 | 10 / 15006 | 55.578 | 0.004 |
| IPR046341 | Homologous_superfamily:SET domain superfamily | 4 / 81 | 40 / 15006 | 18.526 | 0.013 |
| IPR028889 | Domain:Ubiquitin specific protease USP, catalytic domain | 4 / 81 | 41 / 15006 | 18.074 | 0.013 |
| IPR013083 | Homologous_superfamily:Zinc finger, RING/FYVE/PHD-type | 8 / 81 | 262 / 15006 | 5.657 | 0.014 |
| IPR050185 | Family:Ubiquitin carboxyl-terminal hydrolase | 3 / 81 | 17 / 15006 | 32.693 | 0.016 |
| IPR038765 | Homologous_superfamily:Papain-like cysteine peptidase superfamily | 5 / 81 | 91 / 15006 | 10.179 | 0.020 |
| IPR002893 | Domain:Zinc finger, MYND-type | 2 / 81 | 7 / 15006 | 52.931 | 0.075 |
| IPR043216 | Family:Phosphatidic acid phosphatases-like | 2 / 81 | 7 / 15006 | 52.931 | 0.075 |
| IPR063784 | Domain:Sporulation-specific protein 1, conserved domain | 2 / 81 | 7 / 15006 | 52.931 | 0.075 |
| IPR001214 | Domain:SET domain | 3 / 81 | 32 / 15006 | 17.368 | 0.080 |
| IPR001841 | Domain:Zinc finger, RING-type | 5 / 81 | 135 / 15006 | 6.861 | 0.092 |
| IPR001394 | Domain:Peptidase C19, ubiquitin carboxyl-terminal hydrolase | 3 / 81 | 39 / 15006 | 14.251 | 0.130 |
| IPR029044 | Homologous_superfamily:Nucleotide-diphospho-sugar transferases | 4 / 81 | 95 / 15006 | 7.8 | 0.178 |
| IPR000326 | Domain:Phosphatidic acid phosphatase type 2/haloperoxidase | 2 / 81 | 14 / 15006 | 26.466 | 0.237 |
| IPR001012 | Domain:UBX domain | 2 / 81 | 14 / 15006 | 26.466 | 0.237 |
| IPR036938 | Homologous_superfamily:Phosphatidic acid phosphatase type 2/haloperoxidase superfamily | 2 / 81 | 16 / 15006 | 23.157 | 0.297 |
Top 15 GO terms (whole set, family level) — secondary, computational evidence (IEA/IBA) included
15 rows shown, ordered by FDR then p-value; 2 have FDR < 0.05 (bold).
| Term | Name | k / N cand. | n / M bg | Fold | FDR (BH) | GO evidence | Families with non-IEA |
|---|---|---|---|---|---|---|---|
| GO:0060963 | biological_process:positive regulation of ribosomal protein gene transcription by RNA polymerase II | 4 / 42 | 21 / 12533 | 56.839 | 0.003 | has_non_IEA | 1 |
| GO:0060962 | biological_process:regulation of ribosomal protein gene transcription by RNA polymerase II | 4 / 42 | 38 / 12533 | 31.411 | 0.015 | has_non_IEA | 1 |
| GO:0016579 | biological_process:protein deubiquitination | 4 / 42 | 66 / 12533 | 18.085 | 0.092 | IEA_only | 0 |
| GO:0016705 | molecular_function:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 4 / 42 | 80 / 12533 | 14.92 | 0.147 | IEA_only | 0 |
| GO:0005686 | cellular_component:U2 snRNP | 3 / 42 | 35 / 12533 | 25.578 | 0.168 | has_non_IEA | 1 |
| GO:0070646 | biological_process:protein modification by small protein removal | 4 / 42 | 92 / 12533 | 12.974 | 0.168 | IEA_only | 0 |
| GO:0008195 | molecular_function:phosphatidate phosphatase activity | 2 / 42 | 11 / 12533 | 54.255 | 0.315 | IEA_only | 0 |
| GO:0004843 | molecular_function:cysteine-type deubiquitinase activity | 3 / 42 | 50 / 12533 | 17.904 | 0.315 | IEA_only | 0 |
| GO:0101005 | molecular_function:deubiquitinase activity | 3 / 42 | 54 / 12533 | 16.578 | 0.351 | IEA_only | 0 |
| GO:0042577 | molecular_function:lipid phosphatase activity | 2 / 42 | 14 / 12533 | 42.629 | 0.398 | IEA_only | 0 |
| GO:0000245 | biological_process:spliceosomal complex assembly | 2 / 42 | 20 / 12533 | 29.84 | 0.747 | IEA_only | 0 |
| GO:0019783 | molecular_function:ubiquitin-like protein peptidase activity | 3 / 42 | 79 / 12533 | 11.332 | 0.792 | IEA_only | 0 |
| GO:0008234 | molecular_function:cysteine-type peptidase activity | 3 / 42 | 91 / 12533 | 9.838 | 1.000 | IEA_only | 0 |
| GO:0005684 | cellular_component:U2-type spliceosomal complex | 3 / 42 | 97 / 12533 | 9.229 | 1.000 | has_non_IEA | 1 |
| GO:0003700 | molecular_function:DNA-binding transcription factor activity | 9 / 42 | 984 / 12533 | 2.729 | 1.000 | has_non_IEA | 1 |
Actin cytoskeleton controls
Known actin-related families and how many of their proteins pass each filter. Protein ID columns are left out.
| control | pfam_ids | desc_regex | OUT_universe | OUT_in_matrix | OUT_pass_outgroup_rule | candidates | near_miss_in1 | near_miss_in2 | n_Candalbi | n_Candtrop | n_Loddelon | n_Meyeguil | n_Debahans | n_Schestip | n_Spatpass | n_Diutrugo | n_Komaphaf | n_Ogatpara | n_Kuracaps | n_Pichkudr | n_Pachtann | n_Candauri | n_Candhaem | n_Candpseu | n_Candduob | n_Clavlusi | n_Sunginte | n_Metsbicu | n_Metsaff | n_Austsaop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Arp2/3 ARPC2 (P34-Arc) | PF04045 | 13 | 13 | 13 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |
| Arp2/3 ARPC3 (P21-Arc) | PF04062 | 13 | 13 | 13 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |
| Arp2/3 ARPC4 | PF05856 | 13 | 13 | 13 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | |
| Arp2/3 ARPC5 (P16-Arc) | PF04699 | 13 | 13 | 13 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |
| Arp2/3 ARPC1 (description only) | arp2/3 complex.*(41|p41|subunit 1)|ARPC1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |
| Arp2 / Arp3 (description only) | actin-related protein (2|3)\b|\bARP[23]\b | 88 | 88 | 88 | 0 | 0 | 0 | 7 | 7 | 7 | 7 | 6 | 6 | 7 | 7 | 8 | 7 | 7 | 5 | 7 | 6 | 5 | 6 | 7 | 6 | 5 | 4 | 5 | 6 | |
| WAVE complex NCKAP1 | PF09735 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| WAVE complex CYFIP (FragX_IP) | PF05994 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| WAVE complex ABI | PF07815|PF27594 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| SCAR/WAVE (SCAR_helical) | PF27569 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| WASP family (WH1) | PF00568 | 13 | 13 | 13 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |
| WH2 motif (WASP, WAVE, others) | PF02205 | 22 | 22 | 22 | 0 | 0 | 0 | 2 | 3 | 3 | 0 | 2 | 2 | 1 | 2 | 2 | 0 | 2 | 2 | 1 | 2 | 2 | 2 | 2 | 1 | 3 | 1 | 1 | 2 | |
| Formin FH2 | PF02181 | 26 | 26 | 26 | 0 | 0 | 0 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | |
| Formin Drf_GBD / Drf_FH3 / Drf_DAD | PF06371|PF06367|PF06345 | 23 | 23 | 22 | 0 | 0 | 0 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | |
| Ena/VASP (VASP_tetra) | PF08776 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Coronin (description only) | coronin | 9 | 9 | 9 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | |
| Cortactin (HS1_rep) | PF02218 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Myosin 2 tail (Myosin_tail_1) | PF01576 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Myosin head (all myosins) | PF00063 | 40 | 40 | 40 | 0 | 0 | 0 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 4 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 2 | 3 | 3 |
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