generated: '2026-10-24T14:56:58'
study: yc_rev_eremothecium
script:
  path: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/zoosporic_dikarya/analysis/enrichment/enrich_novelties_v2.py
  sha256: d1e8fe16f6842e86fb6c226f822c8c173450a8fec660ca6879a6f8a821ad5aa7
command: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/.pixi/envs/default/bin/python3 /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/zoosporic_dikarya/analysis/enrichment/enrich_novelties_v2.py
  --results /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/results/yc_rev_eremothecium --config /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/config.csv
  --annotations /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations
  --study yc_rev_eremothecium --cache-dir /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/analysis/enrichment/outputs/cache
  --threads 4 --pfam-dat /srv/projects/db/pfam/2026-01-27-Pfam38.2/Pfam-A.hmm.dat --interpro-entries /srv/projects/db/interproscan/6.0.0/110.0/interpro/110.0/entries.json
  --controls /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/zoosporic_dikarya/analysis/enrichment/actin_controls.tsv
  --ingroup-min-frac 0.75 --universe proteome --cluster-background --direction novelty --out-dir /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/analysis/enrichment/outputs/novelty/proteome_clustered
class: ephemeral analysis output (not tracked; regenerate with the command above)
direction: novelty
target_group:
  label: IN
  species:
  - Eremgoss
  - Eremcymb
  - Eremsine
other_group:
  label: OUT
  species:
  - Kluylact
  - Lachther
  - Torudelb
  - Scer
universe: proteome
annotations: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations
annotation_files:
  Eremgoss: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000000591.tsv.gz
  Eremcymb: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000006790.tsv.gz
  Eremsine: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000243052.tsv.gz
  Kluylact: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000000598.tsv.gz
  Lachther: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000002036.tsv.gz
  Torudelb: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000005627.tsv.gz
  Scer: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000002311.tsv.gz
annotation_sources:
  Eremgoss: not recorded (no sidecar)
  Eremcymb: not recorded (no sidecar)
  Eremsine: not recorded (no sidecar)
  Kluylact: not recorded (no sidecar)
  Lachther: not recorded (no sidecar)
  Torudelb: not recorded (no sidecar)
  Scer: not recorded (no sidecar)
vocabulary_coverage:
  pfam:
    species_with_terms:
    - Eremgoss
    - Eremcymb
    - Eremsine
    species_without_terms: []
    n_with: 3
    n_species: 3
  pfam_clan:
    species_with_terms:
    - Eremgoss
    - Eremcymb
    - Eremsine
    species_without_terms: []
    n_with: 3
    n_species: 3
  interpro:
    species_with_terms:
    - Eremgoss
    - Eremcymb
    - Eremsine
    species_without_terms: []
    n_with: 3
    n_species: 3
  go:
    species_with_terms:
    - Eremgoss
    - Eremcymb
    - Eremsine
    species_without_terms: []
    n_with: 3
    n_species: 3
parameters:
  min_bg: 5
  exclude_iea: false
  report_ids_fdr: 0.05
  ingroup_min_frac: 0.75
  other_max_frac: 0.0
  cluster_background: true
statistics: one-sided hypergeometric scipy.stats.hypergeom.sf(k-1,M,n,N); BH (lib/stats_util.bh_fdr) within scope x level
  x vocabulary; scope-B fdr_bh_all_species = BH across species tests of one level x vocabulary. goatools only parses the OBO
  and gives is_a ancestors.
candidate_check:
  matrix_in_rule_and_0_out: 169
  candidates_txt: 169
  symmetric_difference: 0
  candidates_file: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/results/yc_rev_eremothecium/candidates.txt
  presence_matrix: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/results/yc_rev_eremothecium/presence_matrix.uniprot.tsv
  rule: IN count / 3 >= 0.75 and OUT count / 4 <= 0.0 (own proteome counts toward the target group)
  only_in_matrix_rule: []
  only_in_candidates_file: []
background_clustering:
  key: 15990a0a99c54039
  n_sequences: 13542
  n_clusters: 4999
  mmseqs: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/.pixi/envs/default/bin/mmseqs
  mmseqs_version: 18.8cc5c
  command: mmseqs easy-cluster <bg.fa> <out> <tmp> --threads N --min-seq-id 0.3 -c 0.8 --cov-mode 0
  runtime_s: 20.8
  threads: 4
  created: '2026-10-24T14:56:54'
  cache_hit: false
pipeline_candidate_families: 'novelties.<Short>.tsv family_id (nf_NovInvenio MMSEQS_CLUSTER: mmseqs easy-cluster --min-seq-id
  0.3 -c 0.8 --cov-mode 0 on candidates.fa)'
candidates_without_family_row: 0
go_obo:
  path: /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/data/go/go-basic.obo
  data_version: releases/2026-07-26
  sha256: b08d45b268b8c24ccb2513dbbbc7d4df9f6521c099b413f79eb31e06e0fa3bcc
pfam_dat:
  path: /srv/projects/db/pfam/2026-01-27-Pfam38.2/Pfam-A.hmm.dat
  sha256: ead9a40cdb871e1e6ceb151ea15c7aeaff083add2558031b4811afb9d7496b2d
  release_note: release taken from directory name; the .dat file has no version line
interpro_entries: /srv/projects/db/interproscan/6.0.0/110.0/interpro/110.0/entries.json
inputs_sha256:
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/config.csv
  : 09a73ac572da099f076eef129c6bd33673646f536aee3d66ea89138cf94f1c73
  /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/results/yc_rev_eremothecium/candidates.txt: a5a74f71666528747498857a8dd644489b8ac134f0bb0a2a74ebfbf043c0b265
  /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/results/yc_rev_eremothecium/novelties.Eremgoss.tsv: 384a5d20714f5504f41931f8dbf7a5106ab0da6981ed7676094548c7f23f7adf
  /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/results/yc_rev_eremothecium/novelties.Eremcymb.tsv: bdc658cfdfa1f714300d7aca2a247008e15d0ee687b5b4ed1f93eccbd2d12747
  /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/results/yc_rev_eremothecium/novelties.Eremsine.tsv: 4b4138fb4f00919036bd9ce171ad73facc896d4036aa4b4934644105d5eca740
  /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/results/yc_rev_eremothecium/presence_matrix.uniprot.tsv: 0897983ee3fdc5a56167349672e4ec266c1f7279a996783c0d3d10b572a9b795
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/data_dir/pep/UP000000591_284811.pep.fa
  : bc41df7f21fec06918673bda44750ec3ee50f5c508e360f40158fa471f4e688a
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/data_dir/pep/UP000006790_931890.pep.fa
  : 31e02d2ebf667b3f1871657535f46f2711ef69ad67aa44fb1696bc1e4b5c5959
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/data_dir/pep/UP000243052_45286.pep.fa
  : 48f35dffee426c27fe56ae7f1815bd7e39b8dc9b6fb609e8b57dd93e2ca930a8
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/species.csv
  : 7bc3c250ccb58501953ffd4ce3f48ed07caa416c9ccd8582030111501914c00f
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000000591.tsv.gz
  : 27e5e67968a888e408ec7aaba955d94c20c6af32708b9f5945519cb21e13fb53
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000006790.tsv.gz
  : 5831d5fcfd3b8a28e4e6078777975416e8295e2dd3c41a405c300a544c1fc187
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000243052.tsv.gz
  : 5149f9de4ffa7a254079a1bf1423a1ff6edb48ead8f567805c4fafc612f2828a
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000000598.tsv.gz
  : 2d9dd1b5b8bc031eb256c8c5a4606513367fb68594af22ac0b6c481c73ce6860
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000002036.tsv.gz
  : 2d6b71ac9748c00fb4a236986ec21eaf31430733ca9f0db4193c68e0b568586e
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000005627.tsv.gz
  : 125d08fc0e7decdc85807580f1d221ce2c015da8dd36bdd9c64178382eb1c639
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/yeast_convergence/yc_rev_eremothecium/annotations/UP000002311.tsv.gz
  : 83a0c1436d2357898e74c648a772b30ee1cb962e7cca7b975394bde1bb61d690
  ? /bigdata/stajichlab/jstajich/projects/NovInvenio_Investigations/studies/fungi/zoosporic_dikarya/analysis/enrichment/actin_controls.tsv
  : dd7c85c91f413f3eee48b75b51c1ad75f7e2de6afcb611c5e0b3659f777a23d1
tools:
  python: 3.12.14
  scipy: 1.18.1
  goatools: 1.6.4
  mmseqs: 18.8cc5c
runtimes_s:
  load_s: 3.2
  background_cluster_s: 20.9
  tests_s: 2.6
  total_s: 27.6
host: r11
slurm_job: '30452604'
