Files

• Island synteny viewer
• Starships, islands and SM clusters
• Assembly quality QC
• frequency_table (tsv.gz)
• clade_assignments (tsv.gz)
• strain_inventory (tsv.gz)
• significant_islands (tsv.gz)
• island_pfam_enrichment (tsv.gz)
• pangenome_openness (tsv.gz)
• per_strain_summary (tsv.gz)
• classification_counts (tsv.gz)
• island_size_distribution (tsv.gz)
• marker_summary (tsv.gz)
• islands_with_domains (tsv.gz)
• assembly_quality_vs_content (tsv.gz)
• assembly_quality_correlations (tsv.gz)
• diagnostics (tsv.gz)

Pipeline diagnostics

• rescue_redundancy [TRIGGERED]: 7513735/10028130 (74.9%) rescuable cells overlap a predicted gene already assigned to a different family in that strain -- the same locus double-counted, not a genuine annotation dropout (issue #133).
  • prune option: do not enable rescue (--pangenome_rescue_enable false); see clustering sweep #132 before re-enabling
  • prune option: verify --pangenome_rescue_structural_filter is enabled (default true) -- it is the mechanism that removes these cells, not merely detects them
• assembly_quality_confound [TRIGGERED]: max |rho| = 0.42 (rho = 0.4244, accessory_present vs n_contigs (partial, controlling total_length), n = 360 strains); threshold 0.3. See assembly_quality_report.md (issue #130). Between-strain accessory-content comparisons are confounded by assembly fragmentation on this dataset.
  • prune option: exclude or flag the most fragmented assemblies (highest n_contigs in assembly_quality_vs_content.tsv) and rerun
  • prune option: report accessory-content comparisons with assembly quality as a covariate, not as raw per-strain counts
• clade_structure_validity [not computed]: trips when: PCoA1 variance share < ~50%, split-half ARI < 0.8, or between/within clade distance ratio < ~2. Not yet computed by this pipeline -- see #131.
• gain_loss_skew [not computed]: trips when: gain:loss ratio > 20:1 or ambiguous-polarity fraction < 2%. Not yet computed by this pipeline -- see issue #134's calibration reference.

Pangenome report

Definitions

• Gene family: a cluster of proteins from all strains at the tier-1 clustering identity and coverage. A family is present in a strain when a member protein is annotated there, or (with rescue on) when a TBLASTN hit marks it genome_only.
• Frequency class (computed separately for each group, over that group's representative strains): singleton = one representative strain; otherwise by the fraction of representatives: core >= 0.95, soft_core >= 0.90, shell >= 0.15, cloud below 0.15 (defaults; the run parameters set them). A family in no representative gets nonrep_only (only in near-identical strains that were dereplicated away), outgroup_only or ingroup_only (only in the other group), or absent.
• Representative strain: one strain kept per group of near-identical strains (Mash dereplication). Counts of "strains" that include non-representatives are said so.
• Accessory island: a run of consecutive non-core genes in one strain that contains at least one significantly co-occurring pair that is also physically linked. The islands are not tested as units.

Pangenome composition

Ingroup (30950 gene families)

• core: 6371 (20.6%)
• soft_core: 609 (2.0%)
• shell: 4333 (14.0%)
• cloud: 11368 (36.7%)
• singleton: 8269 (26.7%)

Not counted in this group's classes:

• nonrep_only: 3362
• outgroup_only: 1435

Pangenome openness

Heaps' law fit: κ=8332.2, γ=0.244 (R²=0.997) -- pangenome is open (γ > 0; γ = 1 would mean every new strain adds the same number of new families). The curve counts every strain in the presence matrix, including near-identical strains and the outgroup.

Extrapolated asymptotic core-genome size: 686 families.

Per-strain summary

Families per strain: min=8924, median=9408, max=10147 (n=362 strains). See per_strain_summary.tsv for outliers.

Outlier strains (singleton-count modified z-score beyond threshold): TX11, 4545-MICE, 485B-1_L_OLD_CPA0023, GT-101, FMC778, GT-139, VFC084_CPA0067, GT-160, SOIL_604-1_L_OLD_CPA066, VFC083, J_TORRES, UTAH_20380X2, Cocci_1400035797, COCPO_34698, SA14, NACVFR_4542, COCPO_195881, COCPO_4545, NACVFR_2566, 730333_Guatemala, B0858-Guatemala, 730332_Guatemala, 409B-0_L_OLD_CPA0011, UTAH_9443

The outgroup has too few representative genomes to bin on its own; outgroup genomes use ingroup classes.

Ingroup vs outgroup content

Not shown: the outgroup is not binned (too few representative genomes).

Accessory islands

16014 accessory islands found (built from adjacency of non-core genes, gated by containing at least one FDR-significant physically-linked pair). The islands themselves are not tested as units.

Top islands (by size):

9999 single-strain islands excluded (present in one strain only -- strain-private content, which dominates the size ranking).

Locus (strain:contig:start-end)	Genes in island (#)	Span (kb)	Strains (#)	Pfam domains
B0858-Guatemala:scaffold_7:10165-71402	29	61.2	2	AAA_21, AAA_29, ABC_membrane, ABC_tran, APH, BTB, DUF3435, Glyco_tranf_2_3, Glycos_transf_2, HAC6_N, HAC6_helical, HrmA, PK_Tyr_Ser-Thr, Pkinase, RING_XB3-XBAT31, RsgA_GTPase, SMC_N, SRF-TF, zf-C2H2, zf-H2C2_2, zf-RING_2, zf-RING_UBOX
407-1_S_OLD_CPA0004:scaffold_149:1884-51706	27	49.8	2	AIM11_N, ARB_00926, Aa_trans, Acetyltransf_1, Acetyltransf_3, Aspzincin_M35, CBM53, CBM_21, DUF3433, DUF7066, ECH_1, ECH_2, G-patch, G-patch_2, Glyco_hydro_18, PHO4, Peptidase_M35, RRM_1, Tfb5, Yae1_N, Zn_ribbon_RanBP
UTAH_23742X163:scaffold_153:1680-58643	27	57.0	2	ABC_membrane, ABC_tran, APH, Chromo, DUF3435, DUF7924, Glyco_tranf_2_3, Glycos_transf_2, Laminin_I, Patatin, Pkinase, Pkinase_fungal, RsgA_GTPase, SPOK2_N, Shootin
COCPO_195884:scaffold_17:162918-213327	26	50.4	2	AAA, AAA_16, AAA_2, AAA_5, AAA_lid_3, AIM11_N, ARM_ARMC5, ARM_PUB, Acetyltransf_1, Acetyltransf_3, Amidase, Arm, Arm_3, CBM53, CBM_21, DUF7923, DUF815, Glyco_hydro_47, HEAT, HEAT_2, HEAT_EZ, IBB, M20_dimer, MFS_1, MFS_4, MoaE, OB_PRS7, POT1, POT1PC, Peptidase_M20, Prot_ATP_ID_OB_C, RuvB_N, SCO1-SenC, SIL1_FES1_HPBP1_C, SLAC1, TMCO6, TRAP_alpha, Yae1_N, zf-CCCH_12, zf-CCCH_tandem
SDVA42:scaffold_36:10057-69708	26	59.7	2	AAA_21, AAA_29, ABC_membrane, ABC_tran, APH, BTB, DUF3435, Glyco_tranf_2_3, Glycos_transf_2, HAC6_N, HAC6_helical, HrmA, PK_Tyr_Ser-Thr, Pkinase, RING_XB3-XBAT31, RsgA_GTPase, SMC_N, SRF-TF, zf-C2H2, zf-H2C2_2, zf-RING_2, zf-RING_UBOX
407-0_S_OLD_CPA0002:scaffold_36:130365-189967	25	59.6	2	AAA_21, AAA_29, ABC_membrane, ABC_tran, APH, BTB, DUF3435, Glyco_tranf_2_3, Glycos_transf_2, HAC6_N, HAC6_helical, HrmA, PK_Tyr_Ser-Thr, Pkinase, RING_XB3-XBAT31, RsgA_GTPase, SMC_N, SRF-TF, zf-C2H2, zf-H2C2_2, zf-RING_2, zf-RING_UBOX
573-1_S_NEW_CPA0033:scaffold_116:11295-64754	25	53.5	2	AFUB_07903_YDR124W_hel, BTB, BTB_2, HrmA_middle, PK_Tyr_Ser-Thr, Pkinase, Pkinase_fungal, Zn_clus
B10918:scaffold_6:87414-147153	24	59.7	2	AAA_21, AAA_29, ABC_membrane, ABC_tran, APH, BTB, DUF3435, Glyco_tranf_2_3, Glycos_transf_2, HAC6_N, HAC6_helical, HrmA, PK_Tyr_Ser-Thr, Pkinase, RING_XB3-XBAT31, RsgA_GTPase, SMC_N, SRF-TF, zf-C2H2, zf-H2C2_2, zf-RING_2, zf-RING_UBOX
B3341:scaffold_119:1914-37462	20	35.5	2	APH, Abhydrolase_3, BD-FAE, Beta-lactamase, COesterase, Fung_rhodopsin, GGACT, HET, PK_Tyr_Ser-Thr, Pkinase
GT-136:scaffold_132:3810-46411	19	42.6	6	APH, Abhydrolase_3, BD-FAE, Beta-lactamase, COesterase, Fung_rhodopsin, GGACT, HET, PK_Tyr_Ser-Thr, Pkinase
B3352:scaffold_21:235499-274241	18	38.7	2	AAA, AAA_16, AAA_2, AAA_5, AAA_lid_3, ARM_ARMC5, ARM_PUB, Amidase, Arm, Arm_3, DUF7923, DUF815, Glyco_hydro_47, HEAT, HEAT_2, HEAT_EZ, IBB, M20_dimer, MFS_1, MoaE, OB_PRS7, POT1, POT1PC, Peptidase_M20, Prot_ATP_ID_OB_C, RuvB_N, SCO1-SenC, SIL1_FES1_HPBP1_C, SLAC1, TMCO6, TRAP_alpha, zf-CCCH_12, zf-CCCH_tandem
S_674:scaffold_5:146287-190294	17	44.0	4	Chromo, Pkinase
M198:scaffold_7:181911-225908	17	44.0	3	Chromo, Pkinase
M222:scaffold_28:83777-127466	17	43.7	2	Chromo, Pkinase
B5773_Brazil:scaffold_61:29983-64726	16	34.7	5	APH, Beta-lactamase, Fung_rhodopsin, GGACT, HET, PK_Tyr_Ser-Thr, Pkinase
B3236:scaffold_20:131398-166760	16	35.4	2	BTB, Chromo, DUF3435, Pkinase
EMS:scaffold_1:125142-169140	16	44.0	2	Chromo, Pkinase
FMC449:scaffold_1:103831-147516	16	43.7	2	Chromo, Pkinase
B11400:scaffold_3:15125-62015	15	46.9	2	Chromo, Pkinase
B3345:scaffold_122:1716-26579	15	24.9	2	ARB_00926, Aa_trans, Aspzincin_M35, ECH_1, ECH_2, Glyco_hydro_18, PHO4, Peptidase_M35, Tfb5

Pair classification breakdown

• trans: 106620
• trans_unconfirmed: 22940
• unexplained_physical: 10420
• ambiguous_linkage: 3677
• insufficient_data: 3582

Trans-module genomic clustering

Scale: same contig, at least 11 genes apart, gene starts within max 100 kb. Null: accessory genes of the same strain, 200 permutations, seed 0. Pairs on different contigs are excluded, not counted as distant. With millions of pairs a tiny effect still reaches the smallest possible p, so read the effect ratio first.

Module	Families	Strains	Obs. frac (same contig)	Null	Effect	p	Effect (all pairs)	p (all pairs)	Cross-contig excluded
0	1218	362	0.428	0.417	1.03	0.005	0.99	0.995	99.0%
1	1207	362	0.430	0.445	0.96	1.000	1.08	0.005	99.1%
10	145	123	0.989	0.431	2.29	0.005	16.82	0.005	81.2%
100	2	5	-	0.250	-	-	0.00	1.000	100.0%
101	2	12	-	0.364	-	-	0.00	1.000	100.0%
102	2	32	-	0.434	-	-	0.00	1.000	100.0%
103	2	10	0.000	0.444	0.00	1.000	0.00	1.000	50.0%
104	2	5	0.000	0.333	0.00	1.000	0.00	1.000	80.0%
105	2	2	-	-	-	-	-	1.000	100.0%
106	2	7	-	0.333	-	-	0.00	1.000	100.0%
107	2	5	-	0.875	-	-	0.00	1.000	100.0%
108	2	13	-	0.750	-	-	0.00	1.000	100.0%
11	125	360	0.820	0.443	1.85	0.005	47.13	0.005	70.5%
110	2	5	-	0.667	-	-	0.00	1.000	100.0%
111	2	1	-	1.000	-	-	-	-	-%
112	2	4	-	0.833	-	-	0.00	1.000	100.0%
113	2	4	-	0.875	-	-	0.00	1.000	100.0%
114	2	11	-	0.333	-	-	0.00	1.000	100.0%
115	2	5	-	0.667	-	-	0.00	1.000	100.0%
116	2	1	-	-	-	-	-	1.000	100.0%
117	2	5	-	0.364	-	-	0.00	1.000	100.0%
118	2	8	-	0.385	-	-	0.00	1.000	100.0%
119	2	1	-	-	-	-	-	1.000	100.0%
12	24	260	0.034	0.362	0.10	0.985	0.24	0.920	96.6%
120	2	10	-	0.222	-	-	0.00	1.000	100.0%
121	2	9	-	0.444	-	-	0.00	1.000	100.0%
122	2	76	-	0.487	-	-	0.00	1.000	100.0%
123	2	6	-	0.200	-	-	0.00	1.000	100.0%
124	2	7	-	0.273	-	-	0.00	1.000	100.0%
125	2	12	-	0.500	-	-	0.00	1.000	100.0%
126	2	5	-	0.286	-	-	0.00	1.000	100.0%
128	2	5	-	0.429	-	-	0.00	1.000	100.0%
129	2	14	-	0.500	-	-	0.00	1.000	100.0%
13	9	248	0.790	0.406	1.95	0.005	100.49	0.005	30.9%
130	2	26	-	0.385	-	-	0.00	1.000	100.0%
131	2	21	-	0.472	-	-	0.00	1.000	100.0%
132	2	2	-	1.000	-	-	0.00	1.000	100.0%
133	2	7	-	0.333	-	-	0.00	1.000	100.0%
135	2	6	-	0.500	-	-	0.00	1.000	100.0%
136	2	6	-	0.286	-	-	0.00	1.000	100.0%
137	2	4	-	1.000	-	-	0.00	1.000	100.0%
138	2	7	-	0.500	-	-	0.00	1.000	100.0%
139	2	7	-	0.250	-	-	0.00	1.000	100.0%
14	9	214	-	0.440	-	-	0.00	1.000	76.2%
141	2	9	0.000	0.333	0.00	1.000	0.00	1.000	88.9%
142	2	6	-	0.250	-	-	0.00	1.000	100.0%
143	2	4	-	0.778	-	-	0.00	1.000	100.0%
144	2	3	-	0.500	-	-	0.00	1.000	100.0%
145	2	5	1.000	0.000	-	0.143	-	0.005	40.0%
146	2	4	-	0.125	-	-	0.00	1.000	100.0%
148	2	7	-	0.455	-	-	0.00	1.000	100.0%
149	2	6	0.000	0.231	0.00	1.000	0.00	1.000	83.3%
15	7	74	0.000	0.500	0.00	1.000	0.00	1.000	99.4%
150	2	2	-	0.556	-	-	0.00	1.000	100.0%
151	2	9	-	0.455	-	-	0.00	1.000	100.0%
152	2	1	-	-	-	-	-	1.000	100.0%
153	2	8	-	0.364	-	-	0.00	1.000	100.0%
154	2	5	-	0.400	-	-	0.00	1.000	100.0%
155	2	7	-	0.500	-	-	0.00	1.000	100.0%
156	2	10	0.000	0.550	0.00	1.000	0.00	1.000	90.0%
157	2	24	-	0.448	-	-	0.00	1.000	100.0%
158	2	2	-	1.000	-	-	0.00	1.000	100.0%
159	2	1	-	0.000	-	-	-	1.000	100.0%
16	4	6	-	0.750	-	-	0.00	1.000	100.0%
160	2	5	-	0.500	-	-	0.00	1.000	100.0%
162	2	5	-	0.571	-	-	0.00	1.000	100.0%
163	2	15	-	0.269	-	-	0.00	1.000	100.0%
166	2	3	-	0.357	-	-	0.00	1.000	100.0%
167	2	1	-	-	-	-	-	1.000	100.0%
168	2	6	-	0.100	-	-	0.00	1.000	100.0%
169	2	5	-	0.556	-	-	0.00	1.000	100.0%
17	4	109	1.000	0.463	2.16	0.380	298.31	0.005	20.7%
170	2	1	1.000	0.500	2.00	0.667	200.00	0.010	0.0%
171	2	6	-	0.364	-	-	0.00	1.000	100.0%
172	2	1	-	0.500	-	-	0.00	1.000	100.0%
173	2	13	-	0.196	-	-	0.00	1.000	100.0%
174	2	5	-	0.500	-	-	0.00	1.000	100.0%
175	2	6	-	0.643	-	-	0.00	1.000	100.0%
176	2	22	1.000	0.500	2.00	0.481	228.57	0.005	27.3%
177	2	7	-	0.571	-	-	0.00	1.000	100.0%
178	2	7	-	0.200	-	-	0.00	1.000	85.7%
179	2	10	-	0.556	-	-	0.00	1.000	100.0%
18	4	14	-	0.386	-	-	0.00	1.000	63.9%
180	2	1	-	0.667	-	-	0.00	1.000	100.0%
181	2	60	1.000	0.363	2.75	0.333	320.00	0.005	33.3%
182	2	3	-	0.333	-	-	0.00	1.000	100.0%
184	2	11	-	0.556	-	-	0.00	1.000	100.0%
185	2	10	-	0.571	-	-	0.00	1.000	100.0%
186	2	9	-	0.429	-	-	0.00	1.000	100.0%
187	2	175	1.000	0.381	2.63	0.275	153.09	0.005	30.3%
189	2	7	-	0.400	-	-	0.00	1.000	100.0%
19	4	8	0.000	0.438	0.00	1.000	0.00	1.000	65.2%
190	2	1	-	1.000	-	-	0.00	1.000	100.0%
191	2	4	-	0.286	-	-	0.00	1.000	100.0%
192	2	17	-	0.594	-	-	0.00	1.000	100.0%
193	2	6	-	0.500	-	-	0.00	1.000	100.0%
194	2	7	-	0.308	-	-	0.00	1.000	100.0%
195	2	3	-	0.333	-	-	0.00	1.000	100.0%
2	1092	362	0.478	0.522	0.92	1.000	0.70	1.000	99.7%
20	4	38	-	0.413	-	-	0.00	1.000	100.0%
21	4	15	-	0.242	-	-	0.00	1.000	100.0%
22	3	20	-	0.518	-	-	0.00	1.000	100.0%
23	3	51	-	0.397	-	-	0.00	1.000	100.0%
24	3	101	-	0.364	-	-	0.00	1.000	0.0%
25	3	122	-	0.442	-	-	0.00	1.000	53.6%
26	3	5	-	0.500	-	-	0.00	1.000	66.7%
27	3	69	-	0.401	-	-	0.00	1.000	100.0%
28	3	29	-	0.420	-	-	0.00	1.000	100.0%
29	3	98	-	0.377	-	-	0.00	1.000	100.0%
3	703	362	0.393	0.412	0.95	1.000	1.05	0.005	99.0%
31	3	27	-	0.307	-	-	0.00	1.000	100.0%
32	3	18	-	0.619	-	-	0.00	1.000	57.1%
33	3	7	-	0.375	-	-	0.00	1.000	100.0%
34	3	10	-	0.615	-	-	0.00	1.000	66.7%
35	3	15	-	0.441	-	-	0.00	1.000	44.4%
36	3	201	1.000	0.431	2.32	0.299	352.48	0.005	19.5%
37	3	118	0.962	0.415	2.32	0.294	50.00	0.005	86.9%
38	3	42	0.000	0.455	0.00	1.000	0.00	1.000	97.7%
4	551	362	0.682	0.429	1.59	0.005	3.05	0.005	96.7%
40	3	5	-	1.000	-	-	0.00	1.000	100.0%
41	3	45	-	0.490	-	-	0.00	1.000	8.2%
42	3	1	-	0.200	-	-	0.00	1.000	100.0%
43	3	21	-	0.571	-	-	0.00	1.000	100.0%
44	3	11	-	0.417	-	-	0.00	1.000	100.0%
45	3	99	1.000	0.412	2.43	0.228	183.70	0.005	13.1%
46	3	6	0.000	0.167	0.00	1.000	0.00	1.000	83.3%
47	2	94	-	0.425	-	-	0.00	1.000	100.0%
48	2	6	-	0.600	-	-	0.00	1.000	100.0%
49	2	45	-	0.527	-	-	0.00	1.000	100.0%
5	366	362	0.398	0.428	0.93	1.000	0.99	0.682	98.9%
50	2	218	0.000	0.432	0.00	1.000	0.00	1.000	99.5%
51	2	52	1.000	0.421	2.37	0.380	277.78	0.005	3.8%
52	2	4	-	0.500	-	-	0.00	1.000	100.0%
53	2	4	-	0.500	-	-	0.00	1.000	100.0%
54	2	139	-	0.423	-	-	0.00	1.000	100.0%
55	2	4	-	0.429	-	-	0.00	1.000	100.0%
56	2	2	-	0.429	-	-	0.00	1.000	100.0%
57	2	45	-	0.206	-	-	0.00	1.000	100.0%
58	2	24	-	0.462	-	-	0.00	1.000	100.0%
59	2	5	-	0.455	-	-	0.00	1.000	100.0%
6	348	362	0.459	0.431	1.06	0.005	1.13	0.005	99.1%
60	2	3	-	0.000	-	-	-	1.000	100.0%
61	2	44	-	0.484	-	-	0.00	1.000	100.0%
62	2	24	-	0.537	-	-	0.00	1.000	100.0%
63	2	98	0.000	0.432	0.00	1.000	0.00	1.000	99.0%
64	2	5	-	1.000	-	-	0.00	1.000	100.0%
65	2	85	-	0.413	-	-	0.00	1.000	100.0%
66	2	1	-	-	-	-	-	1.000	100.0%
67	2	15	-	0.286	-	-	0.00	1.000	100.0%
68	2	21	-	0.593	-	-	0.00	1.000	100.0%
69	2	102	0.958	0.453	2.12	0.388	215.87	0.005	30.4%
7	344	362	0.983	0.467	2.10	0.005	24.71	0.005	87.0%
70	2	152	1.000	0.401	2.50	0.294	305.13	0.005	21.7%
71	2	8	-	0.600	-	-	0.00	1.000	100.0%
72	2	9	-	0.500	-	-	0.00	1.000	100.0%
73	2	150	1.000	0.396	2.53	0.314	245.95	0.005	39.3%
74	2	260	-	0.380	-	-	0.00	1.000	100.0%
75	2	11	-	0.500	-	-	0.00	1.000	100.0%
76	2	11	-	0.462	-	-	0.00	1.000	100.0%
77	2	3	-	0.286	-	-	0.00	1.000	100.0%
78	2	10	-	0.324	-	-	0.00	1.000	100.0%
79	2	6	-	0.625	-	-	0.00	1.000	100.0%
8	254	362	0.512	0.442	1.16	0.005	1.39	0.005	99.0%
80	2	8	-	0.200	-	-	0.00	1.000	100.0%
81	2	5	-	0.000	-	-	-	1.000	100.0%
82	2	7	0.000	0.250	0.00	1.000	0.00	1.000	57.1%
83	2	5	-	0.429	-	-	0.00	1.000	100.0%
84	2	27	0.000	0.472	0.00	1.000	0.00	1.000	92.6%
85	2	9	-	0.800	-	-	0.00	1.000	100.0%
86	2	1	-	-	-	-	-	1.000	100.0%
87	2	5	-	0.286	-	-	0.00	1.000	100.0%
88	2	9	-	0.400	-	-	0.00	1.000	100.0%
89	2	7	-	0.667	-	-	0.00	1.000	100.0%
9	253	270	0.991	0.404	2.45	0.005	22.84	0.005	81.2%
90	2	4	-	0.667	-	-	0.00	1.000	100.0%
91	2	7	-	0.364	-	-	0.00	1.000	100.0%
92	2	6	-	0.444	-	-	0.00	1.000	100.0%
95	2	3	-	0.000	-	-	-	1.000	100.0%
96	2	6	-	0.429	-	-	0.00	1.000	100.0%
97	2	5	-	0.667	-	-	0.00	1.000	100.0%
98	2	18	-	0.469	-	-	0.00	1.000	100.0%
99	2	8	-	0.429	-	-	0.00	1.000	100.0%

Pfam domain enrichment

Domain	Fisher p	FDR q
DUF3435	4.95e-14	6.56e-11
DUF7924	3.17e-13	2.10e-10
APH	5.29e-10	2.34e-07
MFS_1	5.99e-09	1.99e-06
Sugar_tr	5.80e-07	1.54e-04
Pkinase_fungal	1.06e-06	2.33e-04
Pkinase	1.26e-06	2.39e-04
BTB	1.08e-05	1.59e-03
DUF3723_N	1.08e-05	1.59e-03
DUF3723	7.35e-05	9.73e-03
ABC_membrane	1.09e-04	1.31e-02
PK_Tyr_Ser-Thr	1.39e-04	1.54e-02
NAD_binding_6	1.77e-04	1.69e-02
TRI12	1.79e-04	1.69e-02
AFUB_07903_YDR124W_hel	2.16e-04	1.79e-02
Patatin	2.16e-04	1.79e-02
SPOK2_N	5.87e-04	4.57e-02